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MIT Breakthrough: Once-a-Month Contraceptive Pill Shows Promise in Pig Trials

A survey by OpinionWay for Bayer across nine countries, including France, reveals that 40% of pill users forget at least one dose. Additionally, 20% of 4,500 women aged 21-29 report lapses in weekly adherence. These oversights contribute to unintended pregnancies and abortions. To address this, MIT researchers are developing a monthly contraceptive pill that releases fertility-blocking hormones and withstands stomach acid.

Proven Efficacy in Sow Trials

Tested successfully on sows, this star-shaped pill—about the size of a fish oil capsule—unfolds in the stomach like a six-pointed flower. It gradually releases levonorgestrel, a synthetic progestogen that prevents ovulation, over a full month.

Initial sow trials confirm that daily hormone release matches standard daily pills over four weeks. However, human trials are projected 3-5 years away, according to the researchers.

“Empowering Women with Greater Health Control”

Optimism abounds: “This monthly pill could transform women's health and family planning, particularly in developing countries,” state the MIT team, whose work is funded by the Bill Gates Foundation.
A monthly oral contraceptive offers a discreet, non-invasive option,” notes Kimberly Scarsi, pharmacology professor at the University of Nebraska. It could “boost adherence dramatically, giving women more control over their health and reproductive choices.”