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Underweight and Obesity Both Raise Migraine Risk, Major Neurology Study Finds

Stress, lifestyle choices, sleep deprivation, and genetics are well-known migraine triggers—but new evidence points to body weight extremes as another key factor. In a comprehensive meta-analysis published in the esteemed journal Neurology, researchers reviewed 12 studies involving nearly 300,000 participants. The results show that people with obesity (BMI greater than 30) are 27% more likely to experience migraines than those at a healthy weight. Underweight individuals (BMI less than 18.5) face a 13% higher risk. This connection appears especially pronounced in women and younger adults.

A Mechanism Still Under Investigation

The precise reasons for this weight-migraine link aren't fully understood yet. Adipose tissue, which releases proteins and hormones, is a prime suspect in triggering these headaches. Future studies will explore a critical question: Can targeted weight management—losing excess pounds for the overweight or gaining for the underweight—help reduce migraine frequency?