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Study Finds Adolescent Blood Plasma Sparks Brain Rejuvenation in Aging Mice

Did ancient myths hold a kernel of truth? A groundbreaking study from Alkahest, a leader in therapies targeting cellular and neurological aging, shows adolescent blood plasma can dramatically rejuvenate aging brains. The key lies in the plasma itself.

Prior research demonstrated that young mouse blood injected into older mice restored organs like the liver, heart, and muscles, as detailed by New Scientist. Building on this, Dr. Sakura Minami and her team at Alkahest tested human plasma from 18-year-olds on one-year-old mice—equivalent to 50 human years. These rodents typically show slower movement and memory loss at this stage.

Boosted Vitality Through Neurogenesis

Over three weeks, mice received human plasma injections twice daily. The outcomes were remarkable: treated mice matched the energy of three-month-olds, excelled in maze navigation, and exhibited neurogenesis—new neuron growth in their brains. Dr. Minami identified specific factors in the plasma driving these effects but is reserving details to advance clinical treatments for aging.

Alkahest has launched trials using young donor plasma for Alzheimer's patients.

Exciting progress in age-reversal science.